Detection of immunological markers for Chlamydia trachomatis and Trichomonas vaginalis infection in women with obstetric complications in Najaf, Iraq
Abstract
Infection of female genital tract are associated with many obstetric and gynecological problems include abortion ,intrauterine infection , infertility ,preterm labor and postoperative infection ,in Iraq there is a little study concern with role of both Chlamydia trachomatis , Trichomonas vaginalis and relation with interleukin -6 in different obstetric complications. Hundred women enrolled in this study 60 with different obstetric complications include abortion ,preterm labor and intrauterine death and 40(40%) normal full term pregnancy, full history and examination was done and high vaginal swab was taken for detection of T.vaginalis ( by wet mount preparation and antigen detection).blood was aspirated for detection of antichlamydial antibodies (IgG and IgM) and interleukin-6.The results shows that the diagnosis of T. virginals by antigen detection in vaginal swab more reliable( p<0.001) than direct examination by wet preparation(30.0% and 6.7%) respectively. The presence of C. trachomatis IgG and IgM is (33.3% and 38.3% respectively ) more significant ( p<0.001) in women with obstetric complications in study group than control group (7.5 and 0.0% respectively). The highest level of C. trachomatis IgG and IgM was directly correlated with elevated interleukin -6 (58.3%) in women with obstetric complications.
Infection with T.vaginalis and C. trachomatis were associated with increase risk of abortion, preterm labor and intrauterine death , so screening for both infection may reduce different obstetric complications.
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