Synthesis and Characterization of Some Heterocyclic Compound Tetrazole from Schiff Base

  • Hala Shakier Lihames Al-Shimmery Chemistry department \ Science college\ Babylon university
  • Ferdos Sammie Chemistry department \ Science college\ Babylon university
Keywords: tetrazole, sodium azide, Schiff base.

Abstract

A series of five membered ring, the tetrazole have been synthesized via Schiff base with sodium azide in the -to give the following compounds: o55)C-presence dry acetone at(50
1- 10-Methyl-3,6-bis(5-phenyl-1H-tetrazol-1-yl)-4a,10-dihydroacridine
2- 3,6-bis(5-(3,5-dimethylphenyl)-1H-tetrazol-1-yl)-10-methyl-4a,10-dihydroacridine.
3- 3,6-Bis(5-(2-Bromophenyl)-1H-tetrazol-1-yl)-10-methyl-4a,10- dihydroacridine.
4- 3,6-bis(5-(3-methoxy,5-hydroxyphenyl)-1H-tetrazol-1-yl)-10-methyl-4a,10-dihydroacridine.
The derivatives have long been known to possess hypnotics activity and it is may be to get hypnotics activity from the newly prepared compounds.

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Published
2017-07-07
How to Cite
Lihames Al-Shimmery, H. S., & Sammie, F. (2017). Synthesis and Characterization of Some Heterocyclic Compound Tetrazole from Schiff Base. Al-Qadisiyah Journal of Pure Science, 21(3), 94-103. Retrieved from https://journalsc.qu.edu.iq/index.php/JOPS/article/view/22
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Articles