Study the effects of exposure to gases and vapors in the petroleum refinery in Nasiriyah on liver and Renal functions

  • Ali Abdulhakeem Hassan Albakaa Southern Technical University / Technical Institute Nassiriyah


This study is aimed to study the effects of exposure to petroleum gases and vapors on liver and renal functions in workers in Nasiriyah refinery. The research samples included 30 workers and employees working in two locations. There are two petroleum gases and vapors as sections of production and asphalt refinery in Nasiriyah / Iraq and the study also included a control group of 30 samples from the rest of the refinery sites less exposure to petroleum gases and vapors. The most important finding is conducting tests of liver function [(direct bilirubin, indirect bilirubin and total bilirubin), (tests of liver enzymes Included GOT, GPT, ALP)] and renal tests [blood urea and creatinine] for workers in the sections production and asphalt, where our turned out to be working in sections of production and asphalt were no significant differences  ​​of blood urea when compared with the same testing rates for the control group. While testing rates values ​​ ​​(creatinine, ALT enzyme, AST enzyme, ALP enzyme, direct bilirubin, indirect bilirubin and total bilirubin) were as statistically significant when compared to the same testing rates for the control group. It turns out that workers are not exposed to health syndromes and disorders.


1- Fernando M. C., Annibal M. S. N., João L. B. M., Helma P. C., Ana L. C. N., Alberto S. L. J. e Tatiana O. Bernardo d. C.; (2006); Liver enzyme abnormalities among oil refinery workers; Rev saude publica ; 40 (1); 92-8.
2- عبد علي ،مظهر نبات، جبار. رواء،(2014)، دراسة الصفات الكيموحيوية لمصل العاملية في معمل اسمنت السدة ومعمل الفرات للصناعات الكيمياوية وقائع المؤتمر الرابع لكية التربية للعلوم الصرفة. كلية العلوم للبنات جامعه بابل، العراق، ص465.
3-Ovuru S.S., Berepubo N.A., Nodu M.B.; (2004); Biochemical blood parameters in semi-adult rabbits experimentally fed crude oil contaminated diets; Afr J Biotechnol ;3:343–5.
4-George MI, Adegoke OA;(2011); Effect of vitamin E on biochemical parameters in albino rats treated with gasoline; J Sci Res ;3:641–9.
5-Sirdah, M.M. , Al-laham, A.N, Al, Madhoun, A-R.;(2013): Possible, health effect of liquatied petroleum gas on workers at filling and distribution stations of gaza govetnorates; Eastern Mediterranean health journal; 19 no:3:pp(290).
6-Uboh FE, Akpanabiatu MI, Ndem JI, Alozie Y, Ebong PE.;(2009); Comparative nephrotoxic effect associated with exposure to diesel and gasoline vapours in rats; J Toxicol Environ Health Sci.;1:68–74.
7- Orisakwe E, Njan AA, Afonne OJ, Akumka DD, Orish VN, Udemezue O.O. ;(2004); Investigation into the nephrotoxicity of Nigerian bonny light crude oil in albino rats; In t J Environ Res Public Health; 1:106–10.
8- Kassim, M.H. ;(2012): Effect of fenugreek seeds extract an liver and enzymes of albino male, Iraq journal of science ; 53 number1: page63.
9- (المعهد العربي للصحة والسلامة المهنية -2009)منظمة العمل العربية المعهد العربي للصحة والسلامة المهنية دمشق;2009 ;التسممات المهنية الناجمة عن الرصاص ومركباته;142 ;ص 108-109 .
10- J R Pyatt, I Gilmore, P A Mullins;( 2011); Abnormal liver function tests following inadvertent inhalation of volatile hydrocarbons;Thorax ;July 29.
11-- Uhegbu F. O., Imo C. and Ifeanacho N. G.;(2015); Effect of Exposure of Male Albino Rats to Kerosene, Diesel and Petrol on Kidney Function; International Research Journal of Environment Sciences 4(11), 12-18.
12- F. Missoun, M. Slimani and A. Aoues; (2010) ; Toxic effect of lead on kidney function in rat Wistar;African Journal of Biochemistry Research ;4(2),pp;21-27.
13-June Y T Po, J Mark FitzGerald, Chris Carlsten;( 2011); Respiratory disease associated with solid biomass fuel exposure in rural women and children: systematic review and meta-analysis; Thorax ;66: 232e239.
14- Adebayo AH, Zeng GZ, Zhang YM, Ji CJ, Akindahunsi AA, Tan1 NH;(2010); Toxicological evaluation of precocene II isolated from Ageratum conyzoides L.(Asteraceae) in Sprague Dawley rats. Afr J Biotechnol ;9:2938–44.
15-O. M. Azeez, R. E. Akhigbe and C. N. Anigbogu; (2013); Oxidative status in rat kidney exposed to petroleum hydrocarbons; J Nat Sci Biol Med ; Jan-Jun; 4(1): 149–154.
16- Hala S. A.-E., Ahmed A. A., Abdel-Hady El-G. and Fagr B. B.; (2015) ; Some Biochemical and Hematological Parameters among Petrol Station Attendants: A Comparative Study; BioMed Research International ; Article ID 418724,6 pages.

How to Cite
ABDULHAKEEM HASSAN ALBAKAA, Ali. Study the effects of exposure to gases and vapors in the petroleum refinery in Nasiriyah on liver and Renal functions. Al-Qadisiyah Journal Of Pure Science, [S.l.], v. 22, n. 3, p. 35 - 43, jan. 2018. ISSN 2411-3514. Available at: <>. Date accessed: 16 dec. 2018.