Synthesis and Characterization of some N-arylhydrazone and Imides derivatives from nalidixic acid

Abstract

    This research comprises the synthesizes of N-Arylhydrazone and Imides derivatives of  Nalidixic acid were prepared by esterification of Nalidixic acid to form  compound (1) then reacted with hydrazine hydrate 99% in ethanol to yield hydrazide derivative compound (2). The Schiff base (3a-3c) prepared from the corresponding aryl aldehydes with compound (2). Imides derivatives (4-6) were synthesized  by  reaction of compound (2) with appropriate anhydrides .The structures of compounds  have been characterized  by using some spectroscopic methods, ¹HNMR and  FT-IR.