Impact of Fascioliasis on circulating physiological biomarkers of stress and inflammation in cattle
This study was conducted for verifying the effect of liver worm sickness (Fascioliasis) on the general health of the animal, The hematocrits levels, (RBCs) count, Haemoglobin concentration ( Hb ) and packed cell volume (PCV) were also determined in the two groups of beef infected and non-infected with Fascioliasis the inflammatory parameter in liver :glutamic oxaloacetic transaminase (GOT) and glutamate pyruvate transaminase( GPT) were determined in the beef with moderate Fascioliasis and The results of this study were compared between infected animals and non-infected animals. A few have been taken oxidative stress: Superoxide Dismutase (SOD), Glutathione (GSH), Malondialdehyde (MDA) and catalase enzyme (CAT). In both groups, there were some significant contrasts in the levels of GSH, MDA, SOD, CAT and GOT, GPT. For CAT there was a significantly accelerated in its levels in the infected beef in comparison with the non-infection beef. While GSH and MDA there was a decrease in the level of GSH and an accelerated in the level of MDA in compared to non-infected beef respectively. SOD activity was decreased in blood serum of infected beef comparison with non-infected. The findings showed the beef infected with F. spp. were under oxidative stress. In inflammatory parameters were some significant differences in the levels of (GOT, GPT), its showed accelerated in levels with infected animals and normally in non-infected animals. This research reinforces that animals infected with trematodes, which may have effects on the overall health of animals, will be under oxidative stress and inflammation.
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