Histological evaluation of camel colostrum extracts effects as a new biological therapy on auricular cartilage defect healing.
The aim of the present study was to demonstrate the effect of camel colostrum extracts on auricular cartilage defect healing. Iraqi camel colostrum were collected post-parturition at 0, 6 hours, double centrifuged, filtrated and refrigerated until use. Fifteen albino rats were divided randomly into 3 groups;(TG1) treated with colostrum collected directly after birth, (TG2) treated with colostrum collected 6 hours post-parturition, and (TG3) treated with normal saline. Under routine surgical approach, holes were done in their ear cartilages. The diameter of the holes were measured daily for one week. Biopsies were taken at 1, 2, 3 weeks for histological evaluation of cartilages healing. (TG1) showed the superiority of histological evaluation by complete healing between the two edges of chondrocytes in the site of defect, profuse fibrosis with formation of new blood vessels and mild infiltration of inflammatory cells. The results demonstrated that, the camel colostrum extracts had a beneficial therapeutic effects on cartilage defects, which might regarded as a new biological therapy.
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