The present study aimed evaluate serum antibody titer of salmonella typhi in a sample of Iraqi patients and asses its relation with certain socio-epidemiological parameters, This is a prospective study comprised of Seventy-three patients, selected from those attending Al-Azzizyia hospital and Al-Zubaidyia medical center and twenty seven opposite healthy, checked subjects as control. Patients were selected between October 2017 and mars 2018. Five ml blood was collected from each subject into 5ml plain tube, 3 ml blood were allowed to clot and separated by centrifuge, and the resultant serum was used for Widal test and CRP testing. Serum samples were tested using commercial widal kit.The results showed that high Salmonella typhi infection was found in male patients compared to females (37.5%, 25.6%, P > 0.05). Salmonella typhi infection reached the highest level in young age patients (25-45years) compared to other groups (28.0%, 40.5%, 25%, p<0.005), and poor patients compared to patients with good and moderate income, though non-significant. Significantly low infection rate was found in patients with good personal hygiene, and significantly high number of infections in those patients with the lowest number of rooms/ participants’ houses. In conclusion, we found that typhoid fever is like other infectious diseases still influenced greatly by personal hygiene and home crowdedness. ... قراءة المزيد