A comparison between Aloe vera and silver sulfadiazine on second-degree burns in local male rabbits: A Histological study
The present study carried out on fifteen local male rabbits six months in age, the animals divided for three groups five animals for each, after general anesthesia of all animals, the thoracic region was exposed for three seconds to 2 cm2 wide electrical heating rod to reach second-degree burn. The first group exposed to Vaseline only as a sham control group, second group exposed to silver sulfadiazine cream 0.2% and third group exposed to the Aloe vera (85%), all groups treated continuously once time for fifteen days, and specimens collected from affected area during 5,10 and 15 days after treatment for histopathological evaluations. The results of the study revealed semi like frequent healing process in all groups after five days, whereas at the ten days after treatment the second and third groups showed noticeable healing processes than control group, while at fifteen days from treatment the animals treated with Aloe vera showed approximately complete healing process characterized by presence of thick keratinized layer with profuse collagen in the dermis as well as new formation of hair follicle with noticeable hyperplasia of epidermal layers when compared with second and first groups.
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